funding research locally

Natural killer cells

Dr Janine Coombes

Department of Infection Biology, Institute of Infection and Global Health, University of Liverpool


Optimising NK cell cytotoxicity and infiltration of the tumour microenvironment for successful adoptive immunotherapy in cancer

Our immune systems produce ‘natural killer’ cells which help to rid the body of cancers and infections.

In some cancer patients, however, these cells don’t work so well because they aren’t able to penetrate the tough surface of tumours.

This research project, supported by NWCR, is examining these barriers at a molecular level. It is trying to find a way to adapt natural killer cells so that they can break through to cancer cells and kill them – hopefully offering better treatments for a range of cancers.


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