A. Ian Prior.
A. North West Cancer Research Professor of Molecular Oncology.
A. Division of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool.
A. I investigate how communication networks in cells are wired and how they go wrong in cancer. I’m interested in the Ras family of proteins that are mutated in 30% of human cancers and control many important messaging systems responsible for telling cells when to divide and move. In cancers, these systems can end up switched on all of the time resulting in too many cells in the wrong place.
A. The communication network regulated by Ras proteins represents key drug targets for anti-cancer therapies. Sometimes these therapies stop working when the network rewires itself and develops a resistance to these therapies. Understanding how these communications systems work and how they are likely to respond to different drugs means that we will be better at finding the right combinations of drugs which will give the best long-term responses in individual patients.
A. North West Cancer Research currently funds a post-doctoral researcher in my lab who is profiling cancer cell signalling. This funding has helped me develop my research lab here in Liverpool and has helped me to secure further funding from other research agencies that helped develop our research further.
A. I enjoy working with colleagues across a wide range of scientific disciplines and projects. I enjoy the creative challenge of trying to find ways to address the hard questions in our research. I enjoy seeing the people in my lab develop as scientists and hope to see them continue on to successful scientific careers. I hope that my work will one day lead to better treatment options for cancer patients.
A. I have a family that takes up most of my spare time but if I get a free moment I enjoy sketching.
A. If it was easy everyone would do it.